مورد إلكتروني
أعرض في EDS

The effect of danshen-gegen compound formula on in vitro foam cell formation and in vivo antioxidant level.

التفاصيل البيبلوغرافية
العنوان: The effect of danshen-gegen compound formula on in vitro foam cell formation and in vivo antioxidant level.
بيانات النشر: 2007
تفاصيل مُضافة: Wong, Wai Yin.
Chinese University of Hong Kong Graduate School. Division of Chinese Medicine.
نوع الوثيقة: Electronic Resource
مستخلص: Wong, Wai Yin.
Thesis (M.Phil.)--Chinese University of Hong Kong, 2007.
Includes bibliographical references (leaves 92-108).
s in English and Chinese.
Chapter Chapter 1 --- Introduction --- p.1
Chapter 1.1 --- Atherosclerosis --- p.1
Chapter 1.1.1 --- Pathogenesis of Atherosclerosis --- p.2
Chapter 1.1.2 --- Atherosclerosis and Cardiovascular Disease --- p.4
Chapter 1.2 --- Cardiovascular Disease (CVD) --- p.5
Chapter 1.2.1 --- Term Definition --- p.5
Chapter 1.2.2 --- Risk Factors --- p.6
Chapter 1.2.3 --- Current Western Medications --- p.7
Chapter 1.3 --- Reactive Oxygen Species (ROS) --- p.8
Chapter 1.3.1 --- Impact of ROS --- p.8
Chapter 1.3.2 --- "Superoxide Anion Radical, Hydrogen Peroxide, Hydroxyl Radical, Nitric Oxide" --- p.9
Chapter 1.3.3 --- ROS Production by NAD(P)H Oxidases --- p.11
Chapter 1.3.4 --- ROS Production by Mitochondria --- p.12
Chapter 1.3.5 --- Lipid Peroxidation --- p.13
Chapter 1.3.6 --- Other Sources of ROS --- p.15
Chapter 1.4 --- Antioxidants --- p.16
Chapter 1.4.1 --- Superoxide Dismutase (SOD) --- p.16
Chapter 1.4.2 --- Catalase (CAT) --- p.17
Chapter 1.4.3 --- Glutathinoe Peroxidase (GPx) --- p.17
Chapter 1.4.4 --- Glutathione-S-Transferase (GST) --- p.18
Chapter 1.4.5 --- Vitamin E --- p.18
Chapter 1.4.6 --- Vitamin C --- p.19
Chapter 1.5 --- Ageing --- p.19
Chapter 1.6 --- Antioxidants and CVD --- p.21
Chapter 1.7 --- Traditional Chinese Medicine (TCM) --- p.22
Chapter 1.7.1 --- Danshen --- p.23
Chapter 1.7.2 --- Gegen --- p.25
Chapter 1.7.3 --- Danshen-Gegen Compound Formula (DG) --- p.26
Chapter 1.8 --- Aim of Study --- p.27
Chapter Chapter 2 --- In vitro Foam Cells Formation --- p.29
Chapter 2.1 --- Materials and Methods --- p.29
Chapter 2.1.1 --- Materials --- p.29
Chapter 2.1.2 --- Methods --- p.30
Chapter 2.1.2.1 --- Herbal Preparation by Hot Water Extraction --- p.30
Chapter 2.1.2.2 --- Resident Peritoneal Macrophages Preparation --- p.31
Chapter 2.1.2.3 --- "Colorimetric 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl Tetrazolium Bromide (MTT) Assay" --- p.31
Chapter 2.1.2.4 --- DG Effect on in vitro Foam Cells Formation --- p.32
Chapter 2.2 --- Results and Discussion --- p.32
Chapter 2.3 --- Summary --- p.39
Chapter Chapter 3 --- In vivo Antioxidant Level --- p.40
Chapter 3.1 --- DG Effect on in vivo Antioxidant Levels on Young-adult Wistar Rats --- p.40
Chapter 3.1.1 --- Materials and Methods --- p.40
Chapter 3.1.1.1 --- Herbal Preparation by Hot Water Extraction --- p.40
Chapter 3.1.1.2 --- Assay Kits --- p.41
Chapter 3.1.1.3 --- Antibodies for Protein Expression Determination in Organs --- p.41
Chapter 3.1.1.4 --- Animals and Experimental Design --- p.41
Chapter 3.1.1.5 --- Plasma Antioxidants --- p.42
Chapter 3.1.1.6 --- Lipid Peroxidation and Protein Expression in Organs --- p.46
Chapter 3.1.1.7 --- Statistics --- p.52
Chapter 3.1.2 --- Results and Discussion --- p.53
Chapter 3.2 --- DG Effect on in vivo Antioxidant Levels on Middle-aged Wistar Rats --- p.74
Chapter 3.2.1 --- Materials and Methods --- p.75
Chapter 3.2.2 --- Results and Discussion --- p.75
Chapter 3.3 --- Summary --- p.87
Chapter Chapter 4 --- Conclusion and Future Work --- p.90
Chapter 4.1 --- Conclusion --- p.90
Chapter 4.2 --- Future work --- p.90
Reference --- p.92
Related Publication --- p.109
http://library.cuhk.edu.hk/record=b5893290
Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)
مصطلحات الفهرس: Salvia--Physiological effect, Kudzu--Physiological effect, Antioxidants--Physiological effect, Macrophages--Physiology, Medicine, Chinese, Salvia Miltiorrhiza--physiology, Pueraria--physiology, Antioxidants--physiology, Foam Cells--metabolism, Drugs, Chinese Herbal--therapeutic use, Text, bibliography
URL: https://repository.lib.cuhk.edu.hk/en/item/cuhk-326069
الإتاحة: Open access content. Open access content
Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ملاحظة: print
xiv, 109 leaves : ill. (chiefly col.) ; 30 cm.
English
Chinese
أرقام أخرى: CVU oai:cuhk-dr:cuhk_326069
cuhk:326069
https://repository.lib.cuhk.edu.hk/en/item/cuhk-326069
1365278240
المصدر المساهم: CHINESE UNIV OF HONG KONG
From OAIster®, provided by the OCLC Cooperative.
رقم الأكسشن: edsoai.on1365278240
قاعدة البيانات: OAIster
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