مورد إلكتروني
Investigation of SARS-CoV-2 infection and associated lesions in exotic and companion animals
| العنوان: | Investigation of SARS-CoV-2 infection and associated lesions in exotic and companion animals |
|---|---|
| المؤلفون: | Rotstein, David S., Peloquin, Sarah, Proia, Kathleen, Hart, Ellen, Lee, Jeongha, Vyhnal, Kristin K., Sasaki, Emi, Balamayooran, Gayathriy, Asin, Javier, Southard, Teresa L., Rothfeldt, Laura, Venkat, Heather, Mundschenk, Peter, McDermott, Darby, Crossley, Beate, Ferro, Pamela, Gomez, Gabriel, Henderson, Eileen H., Narayan, Paul, Paulsen, Daniel B., Rekant, Steven, Schroeder, Megan E., Tell, Rachel M., Torchetti, Mia Kim, Uzal, Francisco A., Carpenter, Ann, Ghai, Ria |
| بيانات النشر: | SAGE 2022-01-18 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Documented natural infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in exotic and companion animals following human exposures are uncommon. Those documented in animals are typically mild and self-limiting, and infected animals have only infrequently died or been euthanized. Through a coordinated One Health initiative, necropsies were conducted on 5 animals from different premises that were exposed to humans with laboratory-confirmed SARS-CoV-2 infection. The combination of epidemiologic evidence of exposure and confirmatory real-time reverse transcriptase-polymerase chain reaction testing confirmed infection in 3 cats and a tiger. A dog was a suspect case based on epidemiologic evidence of exposure but tested negative for SARS-CoV-2. Four animals had respiratory clinical signs that developed 2 to 12 days after exposure. The dog had bronchointerstitial pneumonia and the tiger had bronchopneumonia; both had syncytial-like cells with no detection of SARS-CoV-2. Individual findings in the 3 cats included metastatic mammary carcinoma, congenital renal disease, and myocardial disease. Based on the necropsy findings and a standardized algorithm, SARS-CoV-2 infection was not considered the cause of death in any of the cases. Continued surveillance and necropsy examination of animals with fatal outcomes will further our understanding of natural SARS-CoV-2 infection in animals and the potential role of the virus in development of lesions. |
| مصطلحات الفهرس: | bronchopneumonia, dogs, COVID-19, cats, respiratory, severe acute respiratory syndrome coronavirus 2, syncytial cell, viral, tiger, zoonosis, PETS, Lung, Vaccine Related, Prevention, Pneumonia, Biodefense, Emerging Infectious Diseases, Pneumonia & Influenza, Infectious Diseases, Infection, 3 Good Health and Well Being, Article - Refereed |
| URL: | |
| الإتاحة: | Open access content. Open access content http://creativecommons.org/licenses/by/4.0 Creative Commons Attribution 4.0 International |
| ملاحظة: | English |
| أرقام أخرى: | VPI oai:vtechworks.lib.vt.edu:10919/113856 0300-9858 https://doi.org/10.1177/03009858211067467 59 4 Southard, Teresa [0000-0001-8388-7951] 35038930 1544-2217 1375352664 |
| المصدر المساهم: | VIRGINIA TECH From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1375352664 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |