مورد إلكتروني
Frailty and sarcopenia within the earliest national Dutch childhood cancer survivor cohort (DCCSS-LATER):a cross-sectional study
| العنوان: | Frailty and sarcopenia within the earliest national Dutch childhood cancer survivor cohort (DCCSS-LATER):a cross-sectional study |
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| المؤلفون: | van Atteveld, Jenneke E, de Winter, Demi T C, Pluimakers, Vincent G, Fiocco, Marta, Nievelstein, Rutger A J, Hobbelink, Monique G G, Kremer, Leontien C M, Grootenhuis, Martha A, Maurice-Stam, Heleen, Tissing, Wim J E, de Vries, Andrica C H, Loonen, Jacqueline J, van Dulmen-den Broeder, Eline, van der Pal, Helena J H, Pluijm, Saskia M F, van der Heiden-van der Loo, Margriet, Versluijs, A Birgitta, Louwerens, Marloes, Bresters, Dorine, van Santen, Hanneke M, Hoefer, Imo, van den Berg, Sjoerd A A, den Hartogh, Jaap, Hoeijmakers, Jan H J, Neggers, Sebastian J C M M, van den Heuvel-Eibrink, Marry M |
| المصدر: | the Dutch LATER Study group , van Atteveld , J E , de Winter , D T C , Pluimakers , V G , Fiocco , M , Nievelstein , R A J , Hobbelink , M G G , Kremer , L C M , Grootenhuis , M A , Maurice-Stam , H , Tissing , W J E , de Vries , A C H , Loonen , J J , van Dulmen-den Broeder , E , van der Pal , H J H , Pluijm , S M F , van der Heiden-van der Loo , M , Versluijs , A B , Louwerens , M , Bresters , D , van Santen , H M , Hoefer , I , van den Berg , S A A , den Hartogh , J , Hoeijmakers , J H J , Neggers , S J C M M & van den Heuvel-Eibrink , M M 2023 , ' Frailty and sarcopenia within the earliest national Dutch childhood cancer survivor cohort (DCCSS-LATER) : a cross-sectional study ' , The Lancet Healthy Longevity , vol. 4 , no. 4 , pp. e155-e165 . |
| بيانات النشر: | 2023-04 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | BACKGROUND: Childhood cancer survivors appear to be at increased risk of frailty and sarcopenia, but evidence on the occurrence of and high-risk groups for these aging phenotypes is scarce, especially in European survivors. The aim of this cross-sectional study was to assess the prevalence of and explore risk factors for pre-frailty, frailty, and sarcopenia in a national cohort of Dutch childhood cancer survivors diagnosed between 1963 and 2001.METHODS: Eligible individuals (alive at the time of study, living in the Netherlands, age 18-45 years, and had not previously declined to participate in a late-effects study) from the Dutch Childhood Cancer Survivor Study (DCCSS-LATER) cohort were invited to take part in this cross-sectional study. We defined pre-frailty and frailty according to modified Fried criteria, and sarcopenia according to the European Working Group on Sarcopenia in Older People 2 definition. Associations between these conditions and demographic and treatment-related as well as endocrine and lifestyle-related factors were estimated with two separate multivariable logistic regression models in survivors with any frailty measurement or complete sarcopenia measurements.FINDINGS: 3996 adult survivors of the DCCSS-LATER cohort were invited to participate in this cross-sectional study. 1993 non-participants were excluded due to lack of response or a decline to participate and 2003 (50·1%) childhood cancer survivors aged 18-45 years were included. 1114 (55·6%) participants had complete frailty measurements and 1472 (73·5%) participants had complete sarcopenia measurements. Mean age at participation was 33·1 years (SD 7·2). 1037 (51·8%) participants were male, 966 (48·2%) were female, and none were transgender. In survivors with complete frailty measurements or complete sarcopenia measurements, the percentage of pre-frailty was 20·3% (95% CI 18·0-22·7), frailty was 7·4% (6·0-9·0), and sarcopenia was 4·4% (3·5-5·6). In the models for pre-frai |
| مصطلحات الفهرس: | dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being; name=SDG 3 - Good Health and Well-being, article |
| URL: | |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | application/pdf English |
| أرقام أخرى: | QGQ oai:pure.eur.nl:publications/544143a6-4925-445e-a5e6-67cbb82a06f9 https://pure.eur.nl/en/publications/544143a6-4925-445e-a5e6-67cbb82a06f9 https://doi.org/10.1016/S2666-7568(23)00020-X https://pure.eur.nl/ws/files/87692760/Frailty_and_sarcopenia_within_the_earliest_national_Dutch_childhood_cancer_survivor_cohort_DCCSS_LATER_.pdf 1376785906 |
| المصدر المساهم: | ERASMUS UNIVERSITEIT ROTTERDAM From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1376785906 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |