مورد إلكتروني
Immediate-early gene transcriptional activation in hippocampus CA1 and CA3 does not accurately reflect rapid, pattern completion-based retrieval of context memory.
| العنوان: | Immediate-early gene transcriptional activation in hippocampus CA1 and CA3 does not accurately reflect rapid, pattern completion-based retrieval of context memory. |
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| المؤلفون: | Pevzner, Aleksandr |
| المصدر: | Learning & memory (Cold Spring Harbor, N.Y.); vol 22, iss 1, 1-5; 1072-0502 |
| بيانات النشر: | eScholarship, University of California 2014-01-01 |
| تفاصيل مُضافة: | Pevzner, Aleksandr Guzowski, John F |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | No studies to date have examined whether immediate-early gene (IEG) activation is driven by context memory recall. To address this question, we utilized the context preexposure facilitation effect (CPFE) paradigm. In CPFE, animals acquire contextual fear conditioning through hippocampus-dependent rapid retrieval of a previously formed contextual representation. Despite differences in behavior, we did not find any difference in CA1 or CA3 IEG activity associated with this rapid recall phase when comparing context preexposed and non-pre-exposed groups. These findings indicate that IEG activation in CA1 and CA3 is not an accurate readout of the neural activity associated with hippocampus-dependent rapid memory retrieval. |
| مصطلحات الفهرس: | Animals, Rats, Sprague-Dawley, Electroshock, Freezing Reaction, Cataleptic, Fear, Memory, Genes, Immediate-Early, Male, Transcriptional Activation, CA1 Region, Hippocampal, CA3 Region, Conditioning, Psychological, Behavioral and Social Science, Mental Health, Basic Behavioral and Social Science, Genetics, Neurological, Mental health, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery, article |
| URL: | |
| الإتاحة: | Open access content. Open access content public |
| ملاحظة: | application/pdf Learning & memory (Cold Spring Harbor, N.Y.) vol 22, iss 1, 1-5 1072-0502 |
| أرقام أخرى: | CDLER oai:escholarship.org:ark:/13030/qt05f4r46f qt05f4r46f https://escholarship.org/uc/item/05f4r46f https://escholarship.org/ 1377975269 |
| المصدر المساهم: | UC MASS DIGITIZATION From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1377975269 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |