مورد إلكتروني
Estimating foraging behavior in rodents using a modified paradigm measuring threat imminence dynamics.
العنوان: | Estimating foraging behavior in rodents using a modified paradigm measuring threat imminence dynamics. |
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المؤلفون: | Meng, X, Chen, P., Veltien, A.A., Palavra, T., In't Veld, S., Grandjean, J., Homberg, J.R. |
المصدر: | Neurobiology of Stress, 28, pp. 100585 |
بيانات النشر: | 2024 |
نوع الوثيقة: | Electronic Resource |
مستخلص: | Item does not contain fulltext Animals need to respond to threats to avoid danger and approach rewards. In nature, these responses did not evolve alone but are always accompanied by motivational conflict. A semi-naturalistic threat imminence continuum model models the approach-avoidance conflict and is able to integrate multiple behaviors into a single paradigm. However, its comprehensive application is hampered by the lack of a detailed protocol and data about some fundamental factors including sex, age, and motivational level. Here, we modified a previously established paradigm measuring threat imminence continuum dynamics, involving modifications of training and testing protocols, and utilization of commercial materials combined with open science codes, making it easier to replicate. We demonstrate that foraging behavior is modulated by age, hunger level, and sex. This paradigm can be used to study foraging behaviors in animals in a more naturalistic manner with relevance to human approach-avoid conflicts and associated psychopathologies. 01 januari 2024 |
مصطلحات الفهرس: | All institutes and research themes of the Radboud University Medical Center, Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical Neuroscience, Radboudumc 15: Urological cancers Medical Imaging, Radboudumc 7: Neurodevelopmental disorders DCMN: Donders Center for Medical Neuroscience, Article / Letter to editor |
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الإتاحة: | Open access content. Open access content |
أرقام أخرى: | NLQGE oai:repository.ubn.ru.nl:2066/299959 10.1016/j.ynstr.2023.100585 1414569051 |
المصدر المساهم: | RADBOUD UNIVERSITEIT NAJMEGEN From OAIster®, provided by the OCLC Cooperative. |
رقم الأكسشن: | edsoai.on1414569051 |
قاعدة البيانات: | OAIster |
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