مورد إلكتروني
3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers
| العنوان: | 3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers |
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| بيانات النشر: | Uppsala universitet, Molekylär biofysik Uppsala universitet, Biokemi Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA 2023 |
| تفاصيل مُضافة: | Konold, Patrick E. You, Tong Bielecki, Johan Valerio, Joana Kloos, Marco Westphal, Daniel Bellisario, Alfredo Yenupuri, Tej Varma Wollter, August Koliyadu, Jayanath C. P. Koua, Faisal H. M. Letrun, Romain Round, Adam Sato, Tokushi Mészáros, Petra Monrroy, Leonardo Mutisya, Jennifer Bódizs, Szabolcs Larkiala, Taru Nimmrich, Amke Alvarez, Roberto Adams, Patrick Bean, Richard Ekeberg, Tomas Kirian, Richard A. Martin, Andrew V. Westenhoff, Sebastian Maia, Filipe R. N. C. |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | X-ray free-electron lasers (XFELs) can probe chemical and biological reactions as they unfold with unprecedented spatial and temporal resolution. A principal challenge in this pursuit involves the delivery of samples to the X-ray interaction point in such a way that produces data of the highest possible quality and with maximal efficiency. This is hampered by intrinsic constraints posed by the light source and operation within a beamline environment. For liquid samples, the solution typically involves some form of high-speed liquid jet, capable of keeping up with the rate of X-ray pulses. However, conventional jets are not ideal because of radiation-induced explosions of the jet, as well as their cylindrical geometry combined with the X-ray pointing instability of many beamlines which causes the interaction volume to differ for every pulse. This complicates data analysis and contributes to measurement errors. An alternative geometry is a liquid sheet jet which, with its constant thickness over large areas, eliminates the problems related to X-ray pointing. Since liquid sheets can be made very thin, the radiation-induced explosion is reduced, boosting their stability. These are especially attractive for experiments which benefit from small interaction volumes such as fluctuation X-ray scattering and several types of spectroscopy. Although their use has increased for soft X-ray applications in recent years, there has not yet been wide-scale adoption at XFELs. Here, gas-accelerated liquid sheet jet sample injection is demonstrated at the European XFEL SPB/SFX nano focus beamline. Its performance relative to a conventional liquid jet is evaluated and superior performance across several key factors has been found. This includes a thickness profile ranging from hundreds of nanometres to 60 nm, a fourfold increase in background stability and favorable radiation-induced explosion dynamics at high repetition rates up to 1.13 MHz. Its minute thickness also suggests that ultra |
| مصطلحات الفهرس: | free-electron lasers, injectors, single particles, fast SAX, time-resolved studies, fast WAX, sample delivery, XFELs, Biophysics, Biofysik, Article in journal, info:eu-repo/semantics/article, text |
| DOI: | 10.1107.s2052252523007972 |
| URL: | IUCrJ, 2023, 10:6, s. 662-670 |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | application/pdf English |
| أرقام أخرى: | UPE oai:DiVA.org:uu-516986 0000-0001-5931-0925 0000-0002-8745-9740 0000-0001-8735-0369 0000-0001-5155-4431 0000-0002-5333-419X 0000-0001-5568-5017 0000-0002-0245-3842 0000-0001-8371-9587 0000-0002-0569-5193 0000-0002-0723-8228 0000-0003-3155-3487 0000-0001-8852-9424 0009-0004-4180-1311 0000-0003-0425-2101 0000-0003-0092-2104 0000-0001-7197-3086 0000-0002-6961-8015 0000-0002-2141-438x doi:10.1107/s2052252523007972 PMID 37721770 ISI:001098137800005 1415655818 |
| المصدر المساهم: | UPPSALA UNIV LIBR From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1415655818 |
| قاعدة البيانات: | OAIster |
| DOI: | 10.1107.s2052252523007972 |
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