مورد إلكتروني
أعرض في EDS

Hepatocellular carcinoma surgical and oncological trends in a national multicentric population: the HERCOLES experience

التفاصيل البيبلوغرافية
العنوان: Hepatocellular carcinoma surgical and oncological trends in a national multicentric population: the HERCOLES experience
بيانات النشر: Springer Verlag Italia country:IT 2020
تفاصيل مُضافة: Famularo, S
Donadon, M
Cipriani, F
Ardito, F
Carissimi, F
Perri, P
Iaria, M
Dominioni, T
Zanello, M
Conci, S
Molfino, S
Labarba, G
Ferrari, C
Germani, P
Patauner, S
Pinotti, E
Lodo, E
Garatti, M
Sciannamea, I
Troci, A
Conticchio, M
Floridi, A
Chiarelli, M
Fumagalli, L
Memeo, R
Crespi, M
Antonucci, A
Zimmitti, G
Zanus, G
Zago, M
Frena, A
Tarchi, P
Griseri, G
Ercolani, G
Baiocchi, G
Ruzzenente, A
Jovine, E
Maestri, M
Dallavalle, R
Grazi, G
Giuliante, F
Aldrighetti, L
Torzilli, G
Romano, F
Bernasconi, D
Ciulli, C
Giani, A
Costa, G
Ratti, F
Bellobono, M
Calabrese, F
Cremaschi, E
De Peppo, V
Cucchetti, A
Lazzari, G
Percivale, A
Ciola, M
Sega, V
Frassani, S
Del Vecchio, A
Pennacchi, L
Corleone, P
Cosola, D
Salvador, L
Montuori, M
Famularo S.
Donadon M.
Cipriani F.
Ardito F.
Carissimi F.
Perri P.
Iaria M.
Dominioni T.
Zanello M.
Conci S.
Molfino S.
LaBarba G.
Ferrari C.
Germani P.
Patauner S.
Pinotti E.
Lodo E.
Garatti M.
Sciannamea I.
Troci A.
Conticchio M.
Floridi A.
Chiarelli M.
Fumagalli L.
Memeo R.
Crespi M.
Antonucci A.
Zimmitti G.
Zanus G.
Zago M.
Frena A.
Tarchi P.
Griseri G.
Ercolani G.
Baiocchi G. L.
Ruzzenente A.
Jovine E.
Maestri M.
DallaValle R.
Grazi G. L.
Giuliante F.
Aldrighetti L.
Torzilli G.
Romano F.
Bernasconi D. P.
Ciulli C.
Giani A.
Costa G.
Ratti F.
Bellobono M.
Calabrese F.
Cremaschi E.
De Peppo V.
Cucchetti A.
Lazzari G.
Percivale A.
Ciola M.
Sega V.
Frassani S.
Del Vecchio A.
Pennacchi L.
Corleone P.
Cosola D.
Salvador L.
Montuori M.
نوع الوثيقة: Electronic Resource
مستخلص: Liver surgery is the first line treatment for hepatocarcinoma. Hepatocarcinoma Recurrence on the Liver Study (HERCOLES) Group was established in 2018 with the goal to create a network of Italian centres sharing data and promoting scientific research on hepatocellular carcinoma (HCC) in the surgical field. This is the first national report that analyses the trends in surgical and oncological outcomes. Register data were collected by 22 Italian centres between 2008 and 2018. One hundred sixty-four variables were collected, regarding liver functional status, tumour burden, radiological, intraoperative and perioperative data, histological features and oncological follow-up. 2381 Patients were enrolled. Median age was 70 (IQR 63–75) years old. Cirrhosis was present in 1491 patients (62.6%), and Child-A were 89.9% of cases. HCC was staged as BCLC0-A in almost 50% of cases, while BCLC B and C were 20.7% and 17.9% respectively. Major liver resections were 481 (20.2%), and laparoscopy was employed in 753 (31.6%) cases. Severe complications occurred only in 5%. Postoperative ascites was recorded in 10.5% of patients, while posthepatectomy liver failure was observed in 4.9%. Ninety-day mortality was 2.5%. At 5 years, overall survival was 66.1% and disease-free survival was 40.9%. Recurrence was intrahepatic in 74.6% of cases. Redo-surgery and thermoablation for recurrence were performed up to 32% of cases. This is the most updated Italian report of the national experience in surgical treatment for HCC. This dataset is consistently allowing the participating centres in creating multicentric analysis which are already running with a very large sample size and strong power.
مصطلحات الفهرس: Hepatocarcinoma recurrence, Hepatocellular carcinoma, HERCOLES, Liver surgery, Redo surgery, info:eu-repo/semantics/article
URL: https://hdl.handle.net/10281/446297
info:eu-repo/semantics/altIdentifier/pmid/32170630
info:eu-repo/semantics/altIdentifier/wos/WOS:000545145400025
volume:72
issue:2
firstpage:399
lastpage:411
numberofpages:13
journal:UPDATES IN SURGERY
الإتاحة: Open access content. Open access content
ملاحظة: STAMPA
English
أرقام أخرى: ITBAO oai:boa.unimib.it:10281/446297
10.1007/s13304-020-00733-6
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85081743602
1415731512
المصدر المساهم: BICOCCA OPEN ARCH
From OAIster®, provided by the OCLC Cooperative.
رقم الأكسشن: edsoai.on1415731512
قاعدة البيانات: OAIster
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