مورد إلكتروني
Toward sub-second solution exchange dynamics in flow reactors for liquid-phase transmission electron microscopy
| العنوان: | Toward sub-second solution exchange dynamics in flow reactors for liquid-phase transmission electron microscopy |
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| المؤلفون: | Eusko Jaurlaritza, Diputación Foral de Gipuzkoa, Ministerio de Economía y Competitividad (España), Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Ministerio de Ciencia e Innovación (España), PON Ricerca e Innovazione, Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72], Merkens, Stefan, Tollan, Christopher, De Salvo, Giuseppe, Bejtka, Katarzyna, Fontana, Marco, Chiodoni, Angelica, Kruse, Joscha, Iriarte-Alonso, Maiara A., Grzelczak, Marek, Chuvilin, Andrey |
| بيانات النشر: | Springer Nature 2024 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Liquid-phase transmission electron microscopy is a burgeoning experimental technique for monitoring nanoscale dynamics in a liquid environment, increasingly employing microfluidic reactors to control the composition of the sample solution. Current challenges comprise fast mass transport dynamics inside the central nanochannel of the liquid cell, typically flow cells, and reliable fixation of the specimen in the limited imaging area. In this work, we present a liquid cell concept – the diffusion cell – that satisfies these seemingly contradictory requirements by providing additional on-chip bypasses to allow high convective transport around the nanochannel in which diffusive transport predominates. Diffusion cell prototypes are developed using numerical mass transport models and fabricated on the basis of existing two-chip setups. Important hydrodynamic parameters, i.e., the total flow resistance, the flow velocity in the imaging area, and the time constants of mixing, are improved by 2-3 orders of magnitude compared to existing setups. The solution replacement dynamics achieved within seconds already match the mixing timescales of many ex-situ scenarios, and further improvements are possible. Diffusion cells can be easily integrated into existing liquid-phase transmission electron microscopy workflows, provide correlation of results with ex-situ experiments, and can create additional research directions addressing fast nanoscale processes. |
| مصطلحات الفهرس: | artículo |
| URL: | Publisher's version The underlying dataset has been published as supplementary material of the article in the publisher platform at DOI 10.1038/s41467-024-46842-3 Sí info:eu-repo/grantAgreement/MINECO//MDM-2016-0618 |
| الإتاحة: | Open access content. Open access content http://creativecommons.org/licenses/by/4.0 openAccess |
| ملاحظة: | English |
| أرقام أخرى: | CTK oai:digital.csic.es:10261/360728 Nature Communications 15: 2522 (2024) 10.1038/s41467-024-46842-3 2041-1723 1442728089 |
| المصدر المساهم: | CSIC From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1442728089 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |