دورية أكاديمية
A new method for the determination of the relative affinity of a ligand against various DNA sequences by electrospray ionization mass spectrometry. Application to a polyamide minor groove binder
| العنوان: | A new method for the determination of the relative affinity of a ligand against various DNA sequences by electrospray ionization mass spectrometry. Application to a polyamide minor groove binder |
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| المؤلفون: | Buchmann, W., Boutorine, A., Halby, L., Tortajada, J., De Pauw, Edwin |
| المصدر: | Journal of Mass Spectrometry, 44, 1171-1181 (2009) |
| بيانات النشر: | Wiley, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Mass Spectrometry, DNA, Non covalent interactions, Physical, chemical, mathematical & earth Sciences, Chemistry, Life sciences, Biochemistry, biophysics & molecular biology, Physique, chimie, mathématiques & sciences de la terre, Chimie, Sciences du vivant, Biochimie, biophysique & biologie moléculaire |
| الوصف: | A new method for the determination of the relative affinity of a ligand against various dsDNA sequences is presented by using electrospray ionization time-of-flight mass spectrometry (ESI-QTOF) mass spectrometry. Thismethod does not require knowing the ligand concentration accurately. It allows determination of the relative affinity of a ligand against various dsDNA sequences for 1 : 1 complex stoichiometries in a quick manner without labeling. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501 article |
| اللغة: | English |
| Relation: | http://www.interscience.wiley.com; urn:issn:1076-5174; urn:issn:1096-9888 |
| DOI: | 10.1002/jms.1592 |
| URL الوصول: | https://orbi.uliege.be/handle/2268/21869 |
| حقوق: | restricted access http://purl.org/coar/access_right/c_16ec info:eu-repo/semantics/restrictedAccess |
| رقم الأكسشن: | edsorb.21869 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1002/jms.1592 |
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