دورية أكاديمية
Use of vaccinia rabies recombinant for oral vaccination of wildlife
| العنوان: | Use of vaccinia rabies recombinant for oral vaccination of wildlife |
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| المؤلفون: | Desmettre, P., Languet, B., Chappuis, G., Brochier, B., Thomas, I., Lecocq, J.-P., Kieny, M.-P., Blancou, J., Aubert, M., Artois, M., Pastoret, Paul-Pierre |
| المصدر: | Veterinary Microbiology, 23 (1-4), 227-236 (1990) |
| بيانات النشر: | Elsevier Science, 1990. |
| سنة النشر: | 1990 |
| مصطلحات موضوعية: | Animal, Animals, Wild, Disease Vectors, Rabies, Rabies Vaccines, Vaccination, Vaccines, Synthetic, Vaccinia virus, Animalia, Bos taurus, Canis familiaris, Cavia porcellus, Cricetinae, Felis catus, Oryctolagus cuniculus, Ovis aries, Sus scrofa, Vaccinia, Life sciences, Veterinary medicine & animal health, Sciences du vivant, Médecine vétérinaire & santé animale |
| الوصف: | A vaccinia rabies recombinant virus was contructed and shown to induce the synthesis of rabies virus glycoprotein in infected cells and to induce rabies virus neutralizing antibodies and protection in susceptible animals. Active when orally administered, this recombinant is a good candidate for the development of vaccines for wild animal rabies vectors. This recombinant was found stable, safe for target and non-target animal species, and protective for most of the rabies vectors. After extensive experimental studies conducted under controlled conditions, it as used in limited field trials and in an extensive open field trial. The preliminary results confirmed its basic properties and potential for rabies eradication. © 1990. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501 article |
| اللغة: | English |
| Relation: | urn:issn:0378-1135; urn:issn:1873-2542 |
| DOI: | 10.1016/0378-1135(90)90153-M |
| URL الوصول: | https://orbi.uliege.be/handle/2268/236181 |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess |
| رقم الأكسشن: | edsorb.236181 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1016/0378-1135(90)90153-M |
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