Real-Time, Minimally Invasive, Beat-to-Beat Estimation of End-Systolic Volume Using a Modified End-Systolic Pressure-Volume Relation

التفاصيل البيبلوغرافية
العنوان: Real-Time, Minimally Invasive, Beat-to-Beat Estimation of End-Systolic Volume Using a Modified End-Systolic Pressure-Volume Relation
المؤلفون: Davidson, S. M., Pretty, C., Kamoi, S., Balmer, J., Desaive, Thomas, Geoffrey Chase, J.
المصدر: IFAC-PapersOnLine, 50 (1), 5456-5461 (2017); 20th IFAC world congress, 11-17 juillet 2017
بيانات النشر: Elsevier B.V., 2017.
سنة النشر: 2017
مصطلحات موضوعية: Biomedical Control, Biomedical Systems, Least-Squares Estimation, Medical Applications, Medical Systems, Human health sciences, Anesthesia & intensive care, Sciences de la santé humaine, Anesthésie & soins intensifs
الوصف: Intensive care management of cardiovascular disease and dysfunction, a major and growing issue, would benefit from improved synthesis of continuously monitored, information rich catheter waveforms into clear, relevant cardiac metrics. Volume measurements are rarely taken in intensive care, but advances have been made in approximating cardiac stroke volume using pressure measurements. This paper proposes a method for the minimally invasive, real-time, beat-to-beat estimation of end-systolic volume, with the goal of providing further insight into cardiac volume behavior and access to important metrics such as cardiac preload. This method relies on a modified end-systolic pressure-volume relation, aortic pressure and heart rate data and a brief echocardiography calibration. The method was validated across 11 pigs and 2 protocols, encompassing the progression of sepsis and a variety clinical procedures employed in the management of sepsis. The method demonstrated consistently strong correlation coefficients, with a mean of R = 0.82, and low estimation error, with a mean absolute percentage error of 13.3%. This method thus allows effective estimation of end-systolic volume, providing a more complete picture of cardiac behavior in an intensive care environment in which volume measurements are rarely taken. As such, the method has the potential to benefit clinical decision making and management of cardiovascular disease and dysfunction. © 2017
نوع الوثيقة: conference paper
http://purl.org/coar/resource_type/c_5794
conferenceObject
peer reviewed
اللغة: English
Relation: urn:issn:2405-8971; urn:issn:2405-8963
DOI: 10.1016/j.ifacol.2017.08.1082
URL الوصول: https://orbi.uliege.be/handle/2268/248148
حقوق: open access
http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
رقم الأكسشن: edsorb.248148
قاعدة البيانات: ORBi
الوصف
DOI:10.1016/j.ifacol.2017.08.1082