مؤتمر
Zebrafish Osteoblast Transcriptome reveals genes that encode bone extra cellular matrix proteins which on mutating affect bone development
| العنوان: | Zebrafish Osteoblast Transcriptome reveals genes that encode bone extra cellular matrix proteins which on mutating affect bone development |
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| المؤلفون: | Raman, Ratish, Zappia, Jérémie, Nivelle, Renaud, Bahri, Mohamed Ali, Lavergne, Arnaud, Caetano da Silva Caroline, Degueldre Christian, Ostertag Agnes, Renn, Jörg, Collet Corrine, Plenevaux, Alain, Solal Cohen Martine, Henrotin, Yves, Muller, Marc |
| المصدر: | Deutsche Gesellschaft for Martrixbiologie e.V. 2022 (DGMB 2022), Frankfurt am Main, Germany [DE], 07/09/2022 |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | osteoblasts, danio rerio, zebrafish skeletal development, osteoblast transcriptome, bone extra-cellular martrix proteins, ECM, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire |
| الوصف: | Understanding osteoblast differentiation and their function in bone matrix deposition and mineralization is central to the comprehension of bone development and of various bone pathologies. It is, therefore, crucial to not only follow the expression of some landmark transcription factors or ECM proteins but to also investigate the status of signaling pathways and factors regulating these processes. This can only be achieved by assessing the entire transcriptome of these cells. The aim is to study the osteoblast transcriptome, focusing on the possible existence of specific subpopulations at 4dpf and to investigate the role of the fbln1 and col10a1a genes that encode bone ECM proteins in zebrafish skeletal development indicated in the osteoblast transcriptomic data. |
| نوع الوثيقة: | conference poster not in proceedings http://purl.org/coar/resource_type/c_18co conferencePoster peer reviewed |
| اللغة: | English |
| Relation: | info:eu-repo/grantAgreement/EC/H2020/766347 |
| URL الوصول: | https://orbi.uliege.be/handle/2268/294625 |
| حقوق: | restricted access http://purl.org/coar/access_right/c_16ec info:eu-repo/semantics/restrictedAccess |
| رقم الأكسشن: | edsorb.294625 |
| قاعدة البيانات: | ORBi |
| الوصف غير متاح. |