دورية أكاديمية
Impact of Laryngopharyngeal Reflux on Subjective, Aerodynamic, and Acoustic Voice Assessments of Responder and Nonresponder Patients.
| العنوان: | Impact of Laryngopharyngeal Reflux on Subjective, Aerodynamic, and Acoustic Voice Assessments of Responder and Nonresponder Patients. |
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| المؤلفون: | Lechien, Jérôme R, Finck, Camille, Huet, Kathy, Khalife, Mohamad, Fourneau, Anne-Françoise, Delvaux, Véronique, Piccaluga, Myriam, Harmegnies, Bernard, Saussez, Sven |
| المصدر: | Journal of Voice, 33 (6), 929 - 939 (2019-11) |
| بيانات النشر: | Mosby Inc., 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Acoustic, Laryngitis, Laryngopharyngeal, Quality of life, Reflux, Voice, Proton Pump Inhibitors, Pantoprazole, Dysphonia/diagnosis, Dysphonia/etiology, Dysphonia/physiopathology, Female, Humans, Laryngopharyngeal Reflux/complications, Laryngopharyngeal Reflux/diagnosis, Laryngopharyngeal Reflux/physiopathology, Laryngopharyngeal Reflux/therapy, Male, Middle Aged, Pantoprazole/therapeutic use, Prospective Studies, Proton Pump Inhibitors/therapeutic use, Quality of Life, Recovery of Function, Time Factors, Treatment Outcome, Diet, Phonation, Risk Reduction Behavior, Voice Quality, Dysphonia, Laryngopharyngeal Reflux, Otorhinolaryngology, Speech and Hearing, LPN and LVN, Human health sciences, Otolaryngology, Sciences de la santé humaine, Oto-rhino-laryngologie |
| الوصف: | [en] OBJECTIVE: To investigate the usefulness of voice quality assessment as a treatment outcome in responder and nonresponder patients with laryngopharyngeal reflux (LPR).MATERIAL AND METHODS: Eighty clinically diagnosed LPR patients with reflux finding score (RFS) > 7 and reflux symptom index (RSI) > 13 were treated with pantoprazole, lifestyle changes, and diet recommendations for three months. RSI; RFS; Voice Handicap Index; blinded Grade, Roughness, Breathiness, Asthenia, Strain, and Instability; aerodynamic and acoustic measurements were assessed at baseline and after treatment. These data were analyzed and compared with regard to the clinical evolution of patients (responder versus nonresponder). Patients who significantly improved RSI ≤ 13 and RFS ≤ 7 after treatment were considered as responder. Nonresponders were defined as patients with RSI > 13 and/or RFS > 7 at the end of treatment. Studies of correlation between the adherence to the diet regimen and the evolution of both signs and symptoms and between videolaryngostroboscopic signs; blinded Grade, Roughness, Breathiness, Asthenia, Strain, and Instability; and acoustic measurements were conducted.RESULTS: Significant improvements in RSI, RFS, Voice Handicap Index, perceptual voice quality (dysphonia and roughness), and some fundamental frequency and intensity perturbation cues (phonatory fundamental frequency range, percent jitter, pitch perturbation quotient, relative average perturbation, percent shimmer, smoothed amplitude perturbation quotient, amplitude perturbation quotient, and peak-to-peak amplitude variation) were mainly identified after treatment in responder patients. The clinical and voice quality improvements of nonresponder patients were lower; highlighting a similar evolution of symptoms, signs, and voice quality. The correlation analysis revealed significant relationships between the adherence to lifestyle changes and diet recommendations and the improvement of symptoms and substantial correlations between breathiness and fundamental frequency perturbation parameters.CONCLUSION: Voice quality assessments can be used as indicators of the treatment effectiveness in patients with LPR. Voice quality improvement seems to be consistently associated with clinical improvement. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501 article peer reviewed |
| اللغة: | English |
| Relation: | https://api.elsevier.com/content/article/PII:S0892199718300870?httpAccept=text/xml; urn:issn:0892-1997; urn:issn:1873-4588 |
| DOI: | 10.1016/j.jvoice.2018.05.014 |
| URL الوصول: | https://orbi.uliege.be/handle/2268/314322 |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess |
| رقم الأكسشن: | edsorb.314322 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1016/j.jvoice.2018.05.014 |
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