التفاصيل البيبلوغرافية
| العنوان: |
Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds |
| المؤلفون: |
Mitchell Clough, Ichun Anderson Chen, Seong-Wook Park, Allison M. Ahrens, Jeffrey N. Stirman, Spencer L. Smith, Jerry L. Chen |
| المصدر: |
Nature, Nature Communications. 12(1):1-7 |
| سنة النشر: |
2021 |
| الوصف: |
Understanding brain function requires monitoring local and global brain dynamics. Two-photon imaging of the brain across mesoscopic scales has presented trade-offs between imaging area and acquisition speed. We describe a flexible cellular resolution two-photon microscope capable of simultaneous video rate acquisition of four independently targetable brain regions spanning an approximate five-millimeter field of view. With this system, we demonstrate the ability to measure calcium activity across mouse sensorimotor cortex at behaviorally relevant timescales. |
| نوع الوثيقة: |
redif-article |
| اللغة: |
English |
| DOI: |
10.1038/s41467-021-26737 |
| الإتاحة: |
https://ideas.repec.org/a/nat/natcom/v12y2021i1d10.1038_s41467-021-26737-3.html |
| رقم الأكسشن: |
edsrep.a.nat.natcom.v12y2021i1d10.1038.s41467.021.26737.3 |
| قاعدة البيانات: |
RePEc |
