Study protocol for a phase 1/2, single-centre, double-blind, double-dummy, randomized, active-controlled, age de-escalation trial to assess the safety, tolerability and immunogenicity of a measles and rubella vaccine delivered by a microneedle patch in healthy adults (18 to 40 years), measles and rubella vaccine-primed toddlers (15 to 18 months) and measles and rubella vaccine-naïve infants (9 to 10 months) in The Gambia [Measles and Rubella Vaccine Microneedle Patch Phase 1/2 Age De-escalation Trial]

التفاصيل البيبلوغرافية
العنوان:	Study protocol for a phase 1/2, single-centre, double-blind, double-dummy, randomized, active-controlled, age de-escalation trial to assess the safety, tolerability and immunogenicity of a measles and rubella vaccine delivered by a microneedle patch in healthy adults (18 to 40 years), measles and rubella vaccine-primed toddlers (15 to 18 months) and measles and rubella vaccine-naïve infants (9 to 10 months) in The Gambia [Measles and Rubella Vaccine Microneedle Patch Phase 1/2 Age De-escalation Trial]
المؤلفون:	Adigweme, Ikechukwu, Akpalu, Edem, Yisa, Mohammed, Donkor, Simon, Jarju, Lamin B., Danso, Baba, Mendy, Anthony, Jeffries, David, Njie, Abdoulie, Bruce, Andrew, Royals, Michael, Goodson, James L., Prausnitz, Mark R., McAllister, Devin, Rota, Paul A., Henry, Sebastien, Clarke, Ed^{Aff1, IDs13063022064935_cor17}
المصدر:	Trials. 23(1)
قاعدة البيانات:	Springer Nature Journals

الوصف
تدمد:	17456215
DOI:	10.1186/s13063-022-06493-5