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Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors

التفاصيل البيبلوغرافية
العنوان: Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors
المؤلفون: Fried, William, Tyagi, Mrityunjay, Minakhin, Leonid, Chandramouly, Gurushankar, Tredinnick, Taylor, Ramanjulu, Mercy, Auerbacher, William, Calbert, MarissaAff2, Aff4, Rusanov, Timur, Hoang, Trung, Borisonnik, Nikita, Betsch, Robert, Krais, John J., Wang, Yifan, Vekariya, Umeshkumar M.Aff4, Aff9, Gordon, John, Morton, George, Kent, Tatiana, Skorski, TomaszAff4, Aff9, Johnson, Neil, Childers, WayneAff3, Aff10, Chen, Xiaojiang S.Aff1, Aff3, Pomerantz, Richard T.Aff2, Aff3, IDs41467024465931_cor23
المصدر: Nature Communications. 15(1)
قاعدة البيانات: Springer Nature Journals
الوصف
تدمد:20411723
DOI:10.1038/s41467-024-46593-1