The Effect of Salt Concentration and Cation Valency on Interactions Between Mucin-Coated Hydrophobic Surfaces
| العنوان: | The Effect of Salt Concentration and Cation Valency on Interactions Between Mucin-Coated Hydrophobic Surfaces |
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| المؤلفون: | Pettersson, Torbjörn, Feldötö, Zsombor, Claesson, Per M., Dėdinaitė, Andra |
| المصدر: | Progress in Colloid and Polymer Science. 134:1-10 |
| مصطلحات موضوعية: | Adsorption, Atomic force microscope, Cation binding, Mucin, Multivalent ion, Surface force, Swelling, QUARTZ-CRYSTAL MICROBALANCE, ATOMIC-FORCE MICROSCOPE, SOLID-LIQUID INTERFACE, QCM-D, CHROMIUM(III) COMPLEXES, VISCOELASTIC PROPERTIES, GLYCOPROTEINS, WATER, ELLIPSOMETRY, NATURAL SCIENCES, Chemistry, Physical chemistry, Surface and colloid chemistry, NATURVETENSKAP, Kemi, Fysikalisk kemi, Yt- och kolloidkemi |
| الوصف: | The AFM colloidal probe technique has been utilized in order to investigate the forces acting between preadsorbed mucin layers on uncharged, hydrophobic mercaptohexadecane-coated gold surfaces. Layers with some highly extended tails are formed when the adsorption proceeds from 25 ppm mucin solution in 30 mM NaNO3. The effects of salt concentration and cation valency on the interactions have been explored using NaCl, CaCl2, and LaCl3 in the concentration range 1–100 mM. It will be shown that the results in NaCl, where the tail length decreases as the salt concentration is increased, can be rationalized by considering the polyelectrolyte nature of mucin and the screening of intralayer electrostatic interactions between charged groups, mainly anionic sialic acid. When multivalent cations are present in solution a significant compaction of the mucin layer occurs even at low concentrations (1 mM), suggesting binding of these ions to the anionic sites of mucin. The results are discussed in relation to previous data from quartz crystal microbalance measurements on the same systems. |
| وصف الملف: | |
| URL الوصول: | https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-13181 http://www.springerlink.com/content/u5v14861m11m6363/ |
| قاعدة البيانات: | SwePub |
| تدمد: | 0340255X 14378027 |
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| DOI: | 10.1007/2882_2008_075 |