In Silico Phase-Contrast X-Ray Imaging of Anthropomorphic Voxel-Based Phantoms
العنوان: | In Silico Phase-Contrast X-Ray Imaging of Anthropomorphic Voxel-Based Phantoms |
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المؤلفون: | Häggmark, Ilian, Shaker, Kian, Hertz, Hans |
المصدر: | IEEE Transactions on Medical Imaging. 40(2):539-548 |
الوصف: | Propagation-based phase-contrast X-ray imaging is an emerging technique that can improve dose efficiency in clinical imaging. In silico tools are key to understanding the fundamental imaging mechanisms and develop new applications. Here, due to the coherent nature of the phase-contrast effects, tools based on wave propagation (WP) are preferred over Monte Carlo (MC) based methods. WP simulations require very high wave-front sampling which typically limits simulations to small idealized objects. Virtual anthropomorphic voxel-based phantoms are typically provided with a resolution lower than imposed sampling requirements and, thus, cannot be directly translated for use in WP simulations. In the present paper we propose a general strategy to enable the use ofthese phantoms for WP simulations. The strategy is basedon upsampling in the 3D domain followed by projection resulting in high-resolution maps of the projected thickness for each phantom material. These maps can then be efficiently used for simulations of Fresnel diffraction to generate in silico phase-contrast X-ray images. We demonstrate the strategy on an anthropomorphic breast phantom to simulate propagation-based phase-contrast mammography using a laboratory micro-focus X-ray source. |
وصف الملف: | electronic |
URL الوصول: | https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-289582 https://doi.org/10.1109/TMI.2020.3031318 https://kth.diva-portal.org/smash/get/diva2:1525583/FULLTEXT01.pdf |
قاعدة البيانات: | SwePub |
تدمد: | 02780062 1558254X |
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DOI: | 10.1109/TMI.2020.3031318 |