التفاصيل البيبلوغرافية
| العنوان: |
Metabolome Adaptation and Oxidative Stress Response of Common Carp [Cyprinus Carpio] to Altered Water Pollution Levelsmetabolome Adaptation and Oxidative Stress Response of Common Carp [Cyprinus Carpio] to Altered Water Pollution Levels |
| المؤلفون: |
Koubová, Anna |
| المساهمون: |
Van Nguyen, Tuyen (VerfasserIn); Grabicová, Kateřina (VerfasserIn); Burkina, Viktoriia (VerfasserIn); Aydin, Farah Gonul (VerfasserIn); Grabic, Roman (VerfasserIn); Nováková, Petra (VerfasserIn); Švecová, Helena (VerfasserIn); Lepič, Pavel (VerfasserIn); Fedorova, Ganna (VerfasserIn); Randák, Tomáš (VerfasserIn); Žlábek, Vladimír (VerfasserIn) |
| المصدر: |
2022 |
| الناشر: |
[S.l.]: SSRN |
| اللغة: |
English |
| نوع الوثيقة: |
Elektronische Ressource im Fernzugriff |
| Manifestation: |
Monographie [unabhängig ob Stück einer Reihe] |
| مستخلص: |
Treated wastewater ponds (TWPs) serve as recipients and passive tertiary treatment mediators for recycled water. These nutrient-rich habitats are increasingly being recognised for utilisation in aquaculture. Simultaneously, multiple loads of various contaminants with adverse effects on aquatic fauna, including fish, have been recorded. In the present study, we clarified the effects of fish transfer in response to altered levels of pollution on liver metabolic profiles and tissue-specific oxidative stress biomarkers during short- and long-term exposure. In a field experiment, common carp ( Cyprinus carpio ) originating in severely polluted TWP were restocked after one year to a reference pond with a background pollutant concentration typical of the regional river. In contrast, fish that originated in the reference pond were restocked to TWP. Fish were sampled 0, 7, 14, 60, and 180 days after restocking, and tissues were subjected to chemical and biochemical analyses. Pharmaceutically active compounds (PhACs) and metabolic profiles in carp liver were determined using liquid chromatography high-resolution mass spectrometry (LC-HRMS). Oxidative stress biomarkers were evaluated in fish liver, kidney, intestine, and gill. In total, 24 PhACs were detected in the liver with the predominance of antipsychotics. The period of two weeks was sufficient for PhAC elimination from fish metabolism. Restocked fish at both water pollution levels exhibited significant shifts in their liver metabolome. Metabolic acclimation from the TWP to the reference pond lasted until the end of the experiment and was distinguished by high oxidative stress at 14 and 60 days after fish restocking. Fish adaptation to the TWP pollution level took at least 60 days with significant oxidative stress at 7 and 60 days. This study contributed to elucidating the potential risks of fish restocking applied in wastewater reuse for aquaculture |
| رقم الأكسشن: |
EDSZBW1810394929 |
| قاعدة البيانات: |
ECONIS |
