تقرير
Associations between Dietary Habits, Socio-Demographics, and Gut Microbial Composition in Healthy Adolescents
| العنوان: | Associations between Dietary Habits, Socio-Demographics, and Gut Microbial Composition in Healthy Adolescents |
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| اللغة: | English |
| المؤلفون: | Keri M. Kemp (ORCID |
| المصدر: | Grantee Submission. 2023. |
| Peer Reviewed: | Y |
| Page Count: | 13 |
| تاريخ النشر: | 2023 |
| Sponsoring Agency: | Institute of Education Sciences (ED) National Heart, Lung, and Blood Institute (NHLBI) (DHHS/NIH) |
| Contract Number: | R305A180074 1K99HL16509101A1 |
| نوع الوثيقة: | Reports - Research |
| Descriptors: | Dietetics, Eating Habits, Food, Physiology, Adolescents, Nutrition, Socioeconomic Status, Body Composition |
| مصطلحات جغرافية: | Alabama (Birmingham) |
| DOI: | 10.1017/S0007114523002271 |
| مستخلص: | The relationship between dietary habits and microbiota composition during adolescence has not been well examined. This is a crucial knowledge gap to fill considering that diet-microbiota interactions influence neurodevelopment, immune system maturation and metabolic regulation. This study examined the associations between diet and the gut microbiota in a school-based sample of 136 adolescents(M[subscript age] = 12·1 years; age range 11-13 years; 48% female; 47% Black, 38% non-Hispanic White, 15% Hispanic or other minorities) from urban, suburban and rural areas in the Southeast USA. Adolescents completed the Rapid Eating Assessment for Participants and provided stool samples for 16S ribosomal RNA gene sequencing. Parents reported their child and family socio-demographic characteristics. The associations between diet and socio-demographics with gut microbiota diversity and abundance were analyzed using multivariable regression models. Child race and ethnicity, sex, socio-economic status and geographic locale contributed to variation within microbiota composition ([Beta]-diversity). Greater consumption of processed meat was associated with a lower microbial [alpha]-diversity after adjusting for socio-demographic variables. Multi-adjusted models showed that frequent consumption of nutrient-poor, energy-dense foods (e.g. sugar-sweetened beverages, fried foods, sweets) was negatively associated with abundances of genera in the family "Lachnospiraceae" ("Anaerostipes," "Fusicatenibacter" and "Roseburia"), which are thought to play a beneficial role in host health through their production of short-chain fatty acids (SCFAs). These results provide new insights into the complex relationships among socio-demographic factors, diet and gut microbiota during adolescence. Adolescence may represent a critical window of opportunity to promote healthy eating practices that shape a homoeostatic gut microbiota with life-long benefits. [This is the online version of an article published in "British Journal of Nutrition."] |
| Abstractor: | As Provided |
| IES Funded: | Yes |
| Entry Date: | 2024 |
| رقم الأكسشن: | ED641615 |
| قاعدة البيانات: | ERIC |
| DOI: | 10.1017/S0007114523002271 |
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