دورية أكاديمية
أعرض في EDS

Maternal Vitamin D Levels and the Autism Phenotype among Offspring

التفاصيل البيبلوغرافية
العنوان: Maternal Vitamin D Levels and the Autism Phenotype among Offspring
اللغة: English
المؤلفون: Whitehouse, Andrew J. O., Holt, Barbara J., Serralha, Michael
المصدر: Journal of Autism and Developmental Disorders. Jul 2013 43(7):1495-1504.
الإتاحة: Springer. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: service-ny@springer.com; Web site: http://www.springerlink.com
Peer Reviewed: Y
Page Count: 10
تاريخ النشر: 2013
نوع الوثيقة: Journal Articles
Reports - Research
Descriptors: Nutrition, Pregnancy, Prenatal Influences, Autism, Mothers, Pervasive Developmental Disorders, Young Adults, Attention, Symptoms (Individual Disorders)
DOI: 10.1007/s10803-012-1676-8
تدمد: 0162-3257
مستخلص: We tested whether maternal vitamin D insufficiency during pregnancy is related to the autism phenotype. Serum 25(OH)-vitamin D concentrations of 929 women were measured at 18 weeks' pregnancy. The mothers of the three children with a clinical diagnosis of autism spectrum disorder had 25(OH)-vitamin D concentrations above the population mean. The offspring of 406 women completed the Autism-Spectrum Quotient in early adulthood. Maternal 25(OH)-vitamin D concentrations were unrelated to offspring scores on the majority of scales. However, offspring of mothers with low 25(OH)-vitamin D concentrations (<49 nmol/L) were at increased risk for "high" scores (=2SD above mean) on the Attention Switching subscale (odds ratio: 5.46, 95% confidence interval: 1.29, 23.05). The involvement of maternal vitamin D during pregnancy in autism requires continued investigation.
Abstractor: As Provided
Number of References: 35
Entry Date: 2014
رقم الأكسشن: EJ1037809
قاعدة البيانات: ERIC
الوصف
تدمد:0162-3257
DOI:10.1007/s10803-012-1676-8