دورية أكاديمية

A Diagnostic Marker to Discriminate Childhood Apraxia of Speech from Speech Delay: II. Validity Studies of the Pause Marker

التفاصيل البيبلوغرافية
العنوان: A Diagnostic Marker to Discriminate Childhood Apraxia of Speech from Speech Delay: II. Validity Studies of the Pause Marker
اللغة: English
المؤلفون: Shriberg, Lawrence D., Strand, Edythe A., Fourakis, Marios, Jakielski, Kathy J., Hall, Sheryl D., Karlsson, Heather B., Mabie, Heather L., McSweeny, Jane L., Tilkens, Christie M., Wilson, David L.
المصدر: Journal of Speech, Language, and Hearing Research. Apr 2017 60(4):S1118-S1134.
الإتاحة: American Speech-Language-Hearing Association. 2200 Research Blvd #250, Rockville, MD 20850. Tel: 301-296-5700; Fax: 301-296-8580; e-mail: slhr@asha.org; Web site: http://jslhr.pubs.asha.org
Peer Reviewed: Y
Page Count: 17
تاريخ النشر: 2017
Sponsoring Agency: National Institute on Deafness and Other Communication Disorders (NIDCD)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (NIH)
Contract Number: DC000496
HD03352
نوع الوثيقة: Journal Articles
Reports - Research
Descriptors: Delayed Speech, Children, Speech Impairments, Neurological Impairments, Clinical Diagnosis
DOI: 10.1044/2016_JSLHR-S-15-0297
تدمد: 1092-4388
مستخلص: Purpose: The purpose of this 2nd article in this supplement is to report validity support findings for the Pause Marker (PM), a proposed single-sign diagnostic marker of childhood apraxia of speech (CAS). Method: PM scores and additional perceptual and acoustic measures were obtained from 296 participants in cohorts with idiopathic and neurogenetic CAS, adult-onset apraxia of speech and primary progressive apraxia of speech, and idiopathic speech delay. Results: Adjusted for questionable specificity disagreements with a pediatric Mayo Clinic diagnostic standard, the estimated sensitivity and specificity, respectively, of the PM were 86.8% and 100% for the CAS cohort, yielding positive and negative likelihood ratios of 56.45 (95% confidence interval [CI]: [1.15, 2763.31]) and 0.13 (95% CI [0.06, 0.30]). Specificity of the PM for 4 cohorts totaling 205 participants with speech delay was 98.5%. Conclusion: These findings are interpreted as providing support for the PM as a near-conclusive diagnostic marker of CAS.
Abstractor: As Provided
Entry Date: 2017
رقم الأكسشن: EJ1141061
قاعدة البيانات: ERIC
الوصف
تدمد:1092-4388
DOI:10.1044/2016_JSLHR-S-15-0297