دورية أكاديمية
A Diagnostic Marker to Discriminate Childhood Apraxia of Speech from Speech Delay: II. Validity Studies of the Pause Marker
العنوان: | A Diagnostic Marker to Discriminate Childhood Apraxia of Speech from Speech Delay: II. Validity Studies of the Pause Marker |
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اللغة: | English |
المؤلفون: | Shriberg, Lawrence D., Strand, Edythe A., Fourakis, Marios, Jakielski, Kathy J., Hall, Sheryl D., Karlsson, Heather B., Mabie, Heather L., McSweeny, Jane L., Tilkens, Christie M., Wilson, David L. |
المصدر: | Journal of Speech, Language, and Hearing Research. Apr 2017 60(4):S1118-S1134. |
الإتاحة: | American Speech-Language-Hearing Association. 2200 Research Blvd #250, Rockville, MD 20850. Tel: 301-296-5700; Fax: 301-296-8580; e-mail: slhr@asha.org; Web site: http://jslhr.pubs.asha.org |
Peer Reviewed: | Y |
Page Count: | 17 |
تاريخ النشر: | 2017 |
Sponsoring Agency: | National Institute on Deafness and Other Communication Disorders (NIDCD) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (NIH) |
Contract Number: | DC000496 HD03352 |
نوع الوثيقة: | Journal Articles Reports - Research |
Descriptors: | Delayed Speech, Children, Speech Impairments, Neurological Impairments, Clinical Diagnosis |
DOI: | 10.1044/2016_JSLHR-S-15-0297 |
تدمد: | 1092-4388 |
مستخلص: | Purpose: The purpose of this 2nd article in this supplement is to report validity support findings for the Pause Marker (PM), a proposed single-sign diagnostic marker of childhood apraxia of speech (CAS). Method: PM scores and additional perceptual and acoustic measures were obtained from 296 participants in cohorts with idiopathic and neurogenetic CAS, adult-onset apraxia of speech and primary progressive apraxia of speech, and idiopathic speech delay. Results: Adjusted for questionable specificity disagreements with a pediatric Mayo Clinic diagnostic standard, the estimated sensitivity and specificity, respectively, of the PM were 86.8% and 100% for the CAS cohort, yielding positive and negative likelihood ratios of 56.45 (95% confidence interval [CI]: [1.15, 2763.31]) and 0.13 (95% CI [0.06, 0.30]). Specificity of the PM for 4 cohorts totaling 205 participants with speech delay was 98.5%. Conclusion: These findings are interpreted as providing support for the PM as a near-conclusive diagnostic marker of CAS. |
Abstractor: | As Provided |
Entry Date: | 2017 |
رقم الأكسشن: | EJ1141061 |
قاعدة البيانات: | ERIC |
تدمد: | 1092-4388 |
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DOI: | 10.1044/2016_JSLHR-S-15-0297 |