دورية أكاديمية
Vulnerability to Early Stressful Life Events: The Moderating Role of HOMER1 Gene in the Gene x Environment Interaction
| العنوان: | Vulnerability to Early Stressful Life Events: The Moderating Role of HOMER1 Gene in the Gene x Environment Interaction |
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| اللغة: | English |
| المؤلفون: | Chen, Yidi, Wang, Lizhong, Jiang, Dongdong, Zhu, Shanshan, Research Team, WeGene, Chen, Gang, Gan, Yiqun |
| المصدر: | European Journal of Developmental Psychology. 2023 20(1):1-23. |
| الإتاحة: | Routledge. Available from: Taylor & Francis, Ltd. 530 Walnut Street Suite 850, Philadelphia, PA 19106. Tel: 800-354-1420; Tel: 215-625-8900; Fax: 215-207-0050; Web site: http://www.tandf.co.uk/journals |
| Peer Reviewed: | Y |
| Page Count: | 23 |
| تاريخ النشر: | 2023 |
| نوع الوثيقة: | Journal Articles Reports - Research |
| Descriptors: | Foreign Countries, Early Experience, Stress Variables, At Risk Persons, Genetics, Coping, Environmental Influences, Adults |
| مصطلحات جغرافية: | China |
| DOI: | 10.1080/17405629.2021.2011717 |
| تدمد: | 1740-5629 1740-5610 |
| مستخلص: | To explore the curvilinear relationship between early stressful life events and future-oriented coping and whether the "HOMER1" (rs7713917) polymorphism can moderate the relationship between early life stress and two types of future-oriented coping, 14,675 Han Chinese people were surveyed. The relationship between the number of early stressful life events and future-oriented coping adhered to a quadratic curve. "HOMER1" polymorphisms moderated the relationship between the impact of early life stress and preventive coping ([beta] = -0.02, 95% CI [-0.03, -0.01], p = 0.010), which was different from that of proactive coping ([beta] = -0.01, 95% CI [-0.02, 0.01], p = 0.073). Individuals with the AA genotype who experienced a high impact of early life stress were more likely to use preventive coping compared with those who experienced a low level of early life stress, but they showed no difference in their proactive coping strategies. In contrast, individuals with the GA/GG genotype displayed higher vulnerability to environmental changes. |
| Abstractor: | As Provided |
| Entry Date: | 2023 |
| رقم الأكسشن: | EJ1374390 |
| قاعدة البيانات: | ERIC |
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Full Text Finder | تدمد: | 1740-5629 1740-5610 |
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| DOI: | 10.1080/17405629.2021.2011717 |