دورية أكاديمية
Exploring the Genetic Prediction of Academic Underachievement and Overachievement
| العنوان: | Exploring the Genetic Prediction of Academic Underachievement and Overachievement |
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| اللغة: | English |
| المؤلفون: | Kaito Kawakami (ORCID |
| المصدر: | npj Science of Learning. 2024 9. |
| الإتاحة: | Nature Portfolio. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://www.nature.com/npjscilearn/ |
| Peer Reviewed: | Y |
| Page Count: | 11 |
| تاريخ النشر: | 2024 |
| Sponsoring Agency: | National Institutes of Health (NIH) (DHHS) |
| Contract Number: | AG046938 |
| نوع الوثيقة: | Journal Articles Reports - Research |
| Descriptors: | Genetics, Prediction, Academic Achievement, Grade Point Average, Children, Adolescents, Age Differences, Longitudinal Studies, High Achievement, Low Achievement |
| DOI: | 10.1038/s41539-024-00251-9 |
| تدمد: | 2056-7936 |
| مستخلص: | Academic underachievement refers to school performance which falls below expectations. Focusing on the pivotal first stage of education, we explored a quantitative measure of underachievement using genomically predicted achievement delta (GPA[delta]), which reflects the difference between observed and expected achievement predicted by genome-wide polygenic scores. We analyzed the relationship between GPA[delta] at age 7 and achievement trajectories from ages 7 to 16, using longitudinal data from 4175 participants in the Twins Early Development Study to assess empirically the extent to which students regress to their genomically predicted levels by age 16. We found that the achievement of underachievers and overachievers who deviated from their genomic predictions at age 7 regressed on average by one-third towards their genomically predicted levels. We also found that GPA[delta] at age 7 was as predictive of achievement trajectories as a traditional ability-based index of underachievement. Targeting GPA[delta] underachievers might prove cost-effective because such interventions seem more likely to succeed by going with the genetic flow rather than swimming upstream, helping GPA[delta] underachievers reach their genetic potential as predicted by their GPS. However, this is a hypothesis that needs to be tested in intervention research investigating whether GPA[delta] underachievers respond better to the intervention than other underachievers. We discuss the practicality of genomic indices in assessing underachievement. |
| Abstractor: | As Provided |
| Entry Date: | 2024 |
| رقم الأكسشن: | EJ1431726 |
| قاعدة البيانات: | ERIC |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 2056-7936 |
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| DOI: | 10.1038/s41539-024-00251-9 |