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The Portland Neurotoxicity Scale: Validation of a Brief Self-Report Measure of Antiepileptic-Drug-Related Neurotoxicity

التفاصيل البيبلوغرافية
العنوان: The Portland Neurotoxicity Scale: Validation of a Brief Self-Report Measure of Antiepileptic-Drug-Related Neurotoxicity
اللغة: English
المؤلفون: Salinsky, Martin C., Storzbach, Daniel
المصدر: Assessment. Mar 2005 12(1):107-117.
الإتاحة: Sage Publications, 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243 (Toll Free); Fax: 800-583-2665 (Toll Free).
Peer Reviewed: Y
Page Count: 11
تاريخ النشر: 2005
نوع الوثيقة: Journal Articles
Reports - Research
Descriptors: Psychometrics, Cognitive Ability, Longitudinal Studies, Control Groups, Cognitive Tests, Test Validity, Epilepsy, Measurement Techniques, Toxicology, Drug Therapy
DOI: 10.1177/1073191104272857
تدمد: 1073-1911
مستخلص: The Portland Neurotoxicity Scale (PNS) is a brief patient-based survey of neurotoxicity complaints commonly encountered with the use of antiepileptic drugs (AEDs). The authors present data on the validity of this scale, particularly when used in longitudinal studies. Participants included 55 healthy controls, 23 epilepsy patient controls, and 86 healthy volunteers who took various AEDs or placebos for 12 weeks as part of randomized, double-blind studies of AED effects on cognitive abilities. Test-retest reliability in the control groups averaged .80 (total score). Test-retest changes in the PNS were sensitive to AED usage in general (p is less than .001) and to each of the five AEDs tested but not to placebo. Test-retest changes in the PNS were strongly correlated with several scales of the Profile of Mood States but only weakly correlated with objective cognitive test measures. The PNS has satisfactory psychometric properties and is sensitive to AED usage in test-retest studies.
Abstractor: Author
Number of References: 36
Entry Date: 2005
رقم الأكسشن: EJ689744
قاعدة البيانات: ERIC
الوصف
تدمد:1073-1911
DOI:10.1177/1073191104272857